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Drug Safety

LAST REVIEWED: April 16, 2012   /  Posted: October 01, 2010
QT Registry
EKG printout.

The Registry for Drug-Induced Arrhythmias, collects information on drug-induced prolongation or elongation of the QT interval. Clinicians can enter data on patients suspected of having QT prolongation, arrythmias, or cardiac arrest due to a drug or drug combination. Information collected through the registry is applied to prevent future cases.

CERT: University of Arizona
LAST REVIEWED: April 16, 2012   /  Posted: October 01, 2010
Clinically Important Drug Interactions Web Tool
Collection of pills.

This Web page contains tables that describe potential management strategies for 16 drug-drug interactions, including the effects (e.g., pharmacokinetic, pharmacokinetic, clinical) and mechanisms of potential drug-drug interaction, the propensity for related drugs to interact, and options for clinical management.  The tables can serve as an educational tool; it is not to be a guide for medical practice. 

CERT: University of Arizona
LAST REVIEWED: April 16, 2012   /  Posted: October 01, 2010
QT Drug Lists by Risk Group
EKG printout with pills.

This Web page includes 4 drug lists grouped by their relative risk of inducing Torsades de Pointes or prolonged QT; a searchable database of drugs by brand and generic names; and a list of links to PubMed for literature searches of listed drugs. These lists are updated quarterly. 

CERT: University of Arizona
LAST REVIEWED: April 16, 2012   /  Posted: October 01, 2010
Overview of Long QT Syndrome and Torsades de Pointes
Picture of a woman.

This overview explains the long QT syndrome and its associated life-threatening arrhythmia, torsades de pointes. Because this syndrome can occur as a life-threatening side-effect of so many medications, the overview has been written for all physicians and health-care providers who must be able to recognize and manage it.

CERT: University of Arizona
LAST REVIEWED: April 16, 2012   /  Posted: October 01, 2010
Causal Diagram of Conditions Leading to Adverse Drug Events in Outpatient Settings
Picture of people in clinic waiting room.

This interactive Web page shows the complex network of causes for adverse drug events from the patient's perspective. It includes evidence summaries and can be used as a tool for education or research.

An article describing this diagram was published in the September 2006 issue of Patient Counseling and Health Education. Read the abstract.

CERT: University of Arizona